Nestled in the heart of Boston’s Back Bay at 160 Commonwealth Ave., Buttermilk & Bourbon delivers Southern-style comfort with a modern twist. Led by nationally-recognized chef Jason Santos, the restaurant brings the spirit of New Orleans and Southern hospitality to the city, combining vibrant flavors, generous portions, and a lively atmosphere.
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Southern Charm Meets Culinary Excellence
From the moment you walk in, the vibe is warm, inviting, and full of energy. Think: house-made biscuits, pork-belly cracklings, oysters, big-batch cocktails, and plenty of bourbon. The menu draws heavily on Southern influences — but it’s firmly rooted in Boston with finesse.
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Menu Highlights Worth Trying
Here are some standout items you’ll want to put on your must-try list:
• Warm Honey Glazed Biscuits — Smoked cinnamon butter & pimento cheese spread: a perfect start.
• Chili Grilled Broccoli — Buttermilk onion dip, pickled radish, garlic crumbs, smoked lemon-pepper kettle chips: fresh with a kick.
• Braised Lamb Stuffed Shells — Wild mushrooms, bourbon demi-glace, collard greens, herb yogurt: rich and elegantly Southern.
• 2 Fried Chicken Sliders — Sweet-tea honey butter, crisp apple slaw, jalapeño jam: fun bite-sized but full of flavor.
• Apple Crumble Bread Pudding — With bourbon apples, oat crumble, caramel custard: dessert done right.
And don’t miss the bourbon-based cocktails, large-batch drinks and hurricane taps — every sip complements the bold food.
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Ambiance & Why It Works
Buttermilk & Bourbon thrives because it combines great food, great atmosphere, and a location that makes sense. Whether you’re out for brunch, dinner, or just cocktails with friends, it ticks the boxes. The dining room feels lively but approachable — perfect for both casual meals and special occasions.
Its central location in Back Bay means it’s easy to incorporate into a full Boston outing: pre-dinner, after a show, or as the main event.
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Tips for Your Visit
• Reservations recommended, especially on weekends or if you’re looking for prime timing.
• Arrive hungry — many dishes are shareable and you’ll want to sample multiple menu items.
• Pair with drinks — given the strong cocktail and bourbon focus, let the drink menu guide you.
• Timing matters — try brunch or early dinner for a slightly calmer vibe; late night picks up energy.
• Plan for parking or transit — Back Bay has options but it’s Boston, so plan ahead.
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Final Word
If you’ve been looking to explore a standout restaurant in Boston that blends Southern soul with urban sophistication, Buttermilk & Bourbon is a strong contender. From inventive dishes to cocktails that hit the mark, it offers a memorable dining experience that doesn’t feel pretentious. Give it a try — your taste buds will thank you.
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Disclosure: This article is independently written and is not sponsored or affiliated with Buttermilk & Bourbon.

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